3 years ago

Validation of the Chinese version of the Hamilton Rating Scale for Depression in adults with epilepsy

Jiahe Lin, Xinshi Wang, Feirong Dong, Yanru Du, Jingzan Shen, Siqi Ding, Li Wang, Mengqian Ye, Yi Wang, Niange Xia, Rongyuan Zheng, Hong Chen, Huiqin Xu

Publication date: December 2018

Source: Epilepsy & Behavior, Volume 89

Author(s): Jiahe Lin, Xinshi Wang, Feirong Dong, Yanru Du, Jingzan Shen, Siqi Ding, Li Wang, Mengqian Ye, Yi Wang, Niange Xia, Rongyuan Zheng, Hong Chen, Huiqin Xu

Abstract
Objective

This study aimed to validate the Chinese version of the 17-item Hamilton Rating Scale for Depression (C-HRSD-17) for use in adult patients with epilepsy (PWE).

Methods

A consecutive sample of Chinese adult PWE from a tertiary hospital was examined using the C-HRSD-17 and the Mini International Neuropsychiatric Interview (MINI) Plus Chinese Version 5.0.0.

Results

A total of 191 PWE completed the assessment of depression. According to the MINI, thirty patients (15.7%) had current major depressive disorder (MDD). The Cronbach's α coefficient for the C-HRSD-17 was 0.832. Receiver operating characteristic (ROC) analysis showed an area under the curve (AUC) of 0.983 (95% CI = 0.968–0.998). With a cutoff score of 9, the C-HRSD-17 demonstrated the best psychometric properties, with a sensitivity of 96.7%, a specificity of 93.8%, a positive predictive value (PPV) of 74.4%, and a negative predictive value (NPV) of 99.3%.

Conclusion

The C-HRSD-17 proved to be a valid and reliable assessment tool, with a cutoff score of 9 for screening of current MDD in Chinese adult PWE.

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