3 years ago

Identification of proteomic markers in head and neck cancer using MALDI‐MS Imaging, LC‐MS/MS and Immunohistochemistry

Franziska Hoffmann, Claudia Umbreit, Thomas Krüger, Daniela Pelzel, Günther Ernst, Olaf Kniemeyer, Orlando Guntinas-Lichius, Alexander Berndt, Ferdinand von Eggeling

Abstract

Purpose

The heterogeneity of squamous cell carcinoma tissue greatly complicates diagnosis and individualized therapy. Therefore, characterizing the heterogeneity of tissue spatially and identifying appropriate biomarkers is crucial. MALDI imaging (MSI) is capable of analyzing spatially resolved tissue biopsies on a molecular level.

Publisher URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/prca.201700173

DOI: 10.1002/prca.201700173

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