3 years ago

Gelatin Paste as an alternative cost-effective hemostatic agent in cranial surgery: Doing More with Less

Juan Leonardo Serrato-avila, José Omar Navarro-fernández, Rodrigo Hernández-reséndiz, Bernardo Cacho-díaz, Gervith Reyes-soto, Alejandro Monroy-sosa

Publication date: Available online 9 November 2018

Source: World Neurosurgery

Author(s): Juan Leonardo Serrato-Avila, José Omar Navarro-Fernández, Rodrigo Hernández-Reséndiz, Bernardo Cacho-Díaz, Gervith Reyes-Soto, Alejandro Monroy-Sosa


To present an alternative cost-effective hemostatic agent (HA) for cranial surgery, describing the technique to produce it.

Material and Methods

This HA has been used in three reference centers over the last year during 230 procedures including different types of pathology such as skull base, oncology, vascular and trauma, either for endoscopic or open approaches. This agent was made from a low-cost and worldwide available gelatin foam, mixed with saline solution in 2 syringes, connected by a three-way stopcock, making a useful hemostatic paste.


The cost was 16 and 28 times less, compared with Surgiflotm (Ethicon, Johnson and Johnson, N.J., U.S.A.) and Flosealtm (Baxter International, Inc., Deerfield IL) respectively. The median time to prepare the mix was 3 minutes. It was very effective for venous and low-flow bleeding.


The presented technique offers a reliable and cost-effective way of achieving hemostasis in cranial surgery and thus allowing hospitals with limited resources to perform advanced procedures in a safer way.

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