3 years ago

Sellar Atypical Teratoid/Rhabdoid Tumor Presenting with Subarachnoid and Intraventricular Hemorrhage

Karam Asmaro, Muzamil Arshad, Lara Massie, Brent Griffith, Ian Lee

Publication date: Available online 4 November 2018

Source: World Neurosurgery

Author(s): Karam Asmaro, Muzamil Arshad, Lara Massie, Brent Griffith, Ian Lee

Abstract
Background

Atypical teratoid/rhabdoid tumors (ATRT) are uncommon malignancies of the central nervous system and often difficult to distinguish radiographically and pathologically from other common tumors. In this report, we present the first case of sellar ATRT presenting with subarachnoid (SAH) and intraventricular (IVH) hemorrhage.

Case description

A 62 year-old female presented with symptoms of headache, diabetes insipidus, hypothyroidism, and seizures was found to have a sellar tumor with hemorrhagic transformation. Surgical resection was undertaken with pathology consistent with ATRT. Despite early surgical intervention, she later expired before being able to start craniospinal radiation and chemotherapy.

Conclusion

Although known to present with intratumoral hemorrhage, to date no cases of ATRT presenting with SAH or IVH have been reported in the literature. Considering our report that ATRT can present with SAH and IVH, establishing the correct diagnosis via radiographic imaging, gender, pathology and molecular markers is paramount for speedy treatment and management.

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