3 years ago

BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma

Jérôme Moreaux, Bernard Klein, Dirk Hose, Guillaume Cartron, Patrice Ceballos, Salaheddine Bouhya, Anja Seckinger, Laure Vincent, Stéphanie Boireau, Nicolas Robert, Guilhem Requirand

Abstract

Background

Mutiple myeloma (MM) is a neoplasia characterized by the accumulation of malignant plasma cells (PC) in the bone marrow. Although proliferation markers have been studied in MM, none of the current staging systems include them. Moreover, approaches used to analyze proliferation do not separate MM cells (MMCs) from normal PC.

Publisher URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/cyto.b.21730

DOI: 10.1002/cyto.b.21730

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