3 years ago

Aflatoxin biotransformation by commercial peroxidase and its application in contaminated food

Karen Vanessa Marimón Sibaja, Sabrina de Oliveira Garcia, Ana Carla Penteado Feltrin, Rafael Diaz Remedi, Maristela Rodrigues Cerqueira, Eliana Badiale-Furlong, Jaqueline Garda-Buffon

Abstract

BACKGROUND

Aflatoxin B1 (AFB1) is the most commonly occurring and the most toxic of all aflatoxins (AFs). It is responsible for liver cancer in animals and it is listed as a Group I carcinogen by the International Agency for Research on Cancer. Thus, it is necessary to find decontamination methods that show efficiency, specificity, low cost, and that allow the disposal of contaminated raw materials into the environment. This study evaluated the effects of enzyme concentration, pH, temperature and reaction time on AFB1 biotransformation by commercial peroxidase (POD) in a model solution (100 mM phosphate buffer).

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