Palate ulcer, uvular destruction and nasal septal perforation caused by Sporothrix brasiliensis in an HIV-infected patient
Publication date: Available online 12 November 2018
Source: Medical Mycology Case Reports
Author(s): Walter A. Eyer-Silva, Marcelo Costa Velho Mendes de Azevedo, Guilherme Almeida Rosa da Silva, Rodrigo Panno Basílio-de-Oliveira, Luciana Ferreira de Araujo, Isabela Vieira do Lago, Franciele Cristina Ferreira Pereira, Miriã Boaretto Teixeira Fernandes, Maria Helena Galdino Figueiredo-Carvalho, Vanessa Brito de Souza Rabello, Rosely Maria Zancopé-Oliveira, Rodrigo de Almeida-Paes, Fernando Raphael de Almeida Ferry, Rogério Neves-Motta
Sporotrichosis is a human and animal disease caused by dimorphic pathogenic species of the genus Sporothrix. We report a dramatic presentation of Sporothrix brasiliensis infection, with destruction of the nasal septum, soft palate, and uvula of an HIV-infected woman. She was successfully treated with amphotericin B deoxycholate followed by itraconazole. Sporotrichosis remains a neglected opportunistic infection in patients with AIDS and awareness of this potentially fatal infection is of utmost importance.