3 years ago

Factors associated with spousal burden in Parkinson's disease

F. Torny, H. Videaud, P. Chatainier, C. Tarrade, W.g. Meissner, P. Couratier

Publication date: Available online 20 July 2018

Source: Revue Neurologique

Author(s): F. Torny, H. Videaud, P. Chatainier, C. Tarrade, W.G. Meissner, P. Couratier


Parkinson's disease is characterized by motor and non-motor symptoms, which can lead to progressive disability that, in turn, can lead to a burden on caregivers. Thus, the objective of this study was to determine correlations between intensity of disease burden and characteristics of patients and their spouses. The study included 38 couples (patients and spouses) living at home with no severe comorbidities. The following patients’ characteristics were measured: disease severity (MDS-UPDRS); cognitive status (MoCA); non-motor signs (NMSS); quality of life (PDQ-8); anxiety and depression (HADS); and levodopa equivalent dose. The Zarit Burden Interview, quality of life questionnaire (EQ-5D-VAS) and HADS were administered to spouses. The average caregiver burden score was 14.4 ± 12.7, and correlated (in descending order) with severity of non-motor signs (R2 = 0.46, P < 0.0001), anxiety and depression in caregivers and patients (R2 = 0.35, P < 0.0001 and R2 = 0.26, P < 0.0001, respectively), motor severity (R2 = 0.3, P < 0.0001), patients’ quality of life (R2 = 0.27, P = 0.0125), levodopa equivalent dose (R2 = 0.13, P = 0.0261) and duration of illness (R2 = 0.12, P = 0.0307). The severity of non-motor signs, patients’ and caregivers’ mood, and motor disease severity are the main determinants of caregiver burden, making them important targets in the management of Parkinson's disease.

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.