3 years ago

[ASAP] Computational Exploration of a Pd(II)-Catalyzed ?-C–H Arylation Where Stereoselectivity Arises from Attractive Aryl–Aryl Interactions

[ASAP] Computational Exploration of a Pd(II)-Catalyzed ?-C–H Arylation Where Stereoselectivity Arises from Attractive Aryl–Aryl Interactions
Katherine L. Bay, Yun-Fang Yang, K. N. Houk
The enantioselective Pd(II)-catalyzed γ-C–H arylation of picolinamides with a chiral BINOL phosphate ligand was explored using density functional theory (DFT). Enantioselectivity arises from attractive aryl–aryl interactions between the pseudoequatorial phenyl substituent of the substrate and the chiral BINOL phosphate ligand.

Publisher URL: http://dx.doi.org/10.1021/acs.joc.8b02416

DOI: 10.1021/acs.joc.8b02416

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.