Combining culture and microbead‐based immunoassay for the early and generic detection of bacteria in platelet concentrates
Despite current preventive strategies, bacterial contamination of platelets is the highest residual infectious risk in transfusion. Bacteria can grow from an initial concentration of 0.03–0.3 colony‐forming units (CFUs)/mL up to 108 to 109 CFUs/mL over the product shelf life. The aim of this study was to develop a cost‐effective approach for an early, rapid, sensitive, and generic detection of bacteria in platelet concentrates.
Publisher URL: https://onlinelibrary.wiley.com/doi/abs/10.1111/trf.15019