5 years ago

Lithium Use in Pregnancy and the Risk of Cardiac Malformations

Huybrechts, Krista F., Hernandez-Diaz, Sonia, Bateman, Brian T., Cohen, Jacqueline M., Desai, Rishi J., Mogun, Helen, Patorno, Elisabetta, Cohen, Lee S.
(Abstracted from N Engl J Med 2017;376:2245–2254) Lithium is a first-line treatment for women of reproductive age with bipolar disorder. However, concerns persist that exposure increases the risk of congenital cardiac defects including Ebstein anomaly, a right ventricular outflow tract obstruction defect.
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