3 years ago

Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening

Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening
Jing Xing, Hong Ding, Bidong Zhang, Yulan Wang, Yu-Chih Liu, Kaixian Chen, Chenhua Zhang, Ruifeng Mao, Mingyue Zheng, Xiaomin Luo, Bing Zhou, Yaxi Yang, Cheng Luo, Yan Ye, Hualiang Jiang
A series of highly selective and potent inhibitors against PRMT5 have been achieved using virtual screening and medicinal chemistry approaches.

Publisher URL: http://feeds.rsc.org/~r/rss/OB/~3/oYGoedoCB9g/C7OB00070G

DOI: 2017/OB/C7OB00070G

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