5 years ago

Indolylmethanols as Reactants in Catalytic Asymmetric Reactions

Indolylmethanols as Reactants in Catalytic Asymmetric Reactions
Feng Shi, Guang-Jian Mei
Indolylmethanols have emerged as versatile reactants in catalytic asymmetric reactions because of the facile generation of reactive intermediates from these compounds. The most common indolylmethanols are 3-indolylmethanols and 2-indolylmethanols, and the reaction types applicable to these heterocycles mainly include catalytic enantioselective substitutions and cyclizations. Using indolylmethanols as reactants in catalytic asymmetric reactions enables the enantioselective construction of a variety of indole-containing frameworks.

Publisher URL: http://dx.doi.org/10.1021/acs.joc.7b01458

DOI: 10.1021/acs.joc.7b01458

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