Trends in Biochemical Sciences
Trends in Biochemical Sciences
5 years ago

Pro(moting) the Turnover of Gluconeogenic Enzymes by a New Branch of the N-end Rule Pathway

The N-end rule pathway is a set of protein degradation systems that link the in vivo stability of a protein to its N-terminal residue. A recent paper from Alexander Varshavsky’s laboratory [1] identifies a new branch of the N-end rule pathway that specifically recognizes the N-terminal Pro residue of key gluconeogenesis enzymes.

Publisher URL: www.sciencedirect.com/science

DOI: S0968000417300683

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