5 years ago

α,β-Unsaturated Amides as Dipolarophiles: Catalytic Asymmetric exo-Selective 1,3-Dipolar Cycloaddition with Nitrones

α,β-Unsaturated Amides as Dipolarophiles: Catalytic Asymmetric exo-Selective 1,3-Dipolar Cycloaddition with Nitrones
Ming Zhang, Masakatsu Shibasaki, Naoya Kumagai
Invited for the cover of this issue are Ming Zhang, Naoya Kumagai, and Masakatsu Shibasaki at the Institute of Microbial Chemistry (IMC) in Tokyo. The image depicts a hypothetical molecular architecture composed of five-membered heterocycles. Read the full text of the article at 10.1002/chem.201702330. “Manifestation of both endo-selectivity and broad substrate generality has been long awaited in the 1,3-dipolar cycloaddition of nitrones and electron-deficient olefins.” Read more about the story behind the cover in the Cover Profile and about the research itself on page ▪▪ ff. (DOI: 10.1002/chem.201702330).

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201703250

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