3 years ago

Prognostic significance of tumor budding, tumor‐stroma ratio, cell nests size, and stroma type in laryngeal and pharyngeal squamous cell carcinomas

Georgia Karpathiou, Marine Vieville, Marie Gavid, Florian Camy, Jean Marc Dumollard, Nicolas Magné, Marios Froudarakis, Jean Michel Prades, Michel Peoc'h

Abstract

Background

Despite immune microenvironment of head and neck squamous cell carcinoma (HNSCC) has been studied, there are no sufficient data on the role of tumor stroma factors. The aim of the study was to explore the prognostic and predictive role of these factors in a large series of HNSCC.

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