3 years ago

Bimetallic copper and zinc-catalyzed oxidative cycloaddition of 3-aminopyridazines and nitriles: a direct synthesis of 1,2,4-triazolo[1,5-b]pyridazines via C-N and N-N bond-forming process

Bimetallic copper and zinc-catalyzed oxidative cycloaddition of 3-aminopyridazines and nitriles: a direct synthesis of 1,2,4-triazolo[1,5-b]pyridazines via C-N and N-N bond-forming process
Xing-Feng Bai, Chun-Gu Xia, Ji-Yuan Lv, Qiu-Chao Mu, Li-Wen Xu, Jing Chen, Mu-Yi Chen
One-pot formation of 1,2,4-triazolo[1,5-b]pyridazine derivatives is presented in this manuscript, in which the targets are offered via cooperative Cu(I)/Zn(II)-catalyzed tandem C-N addition and I2/KI-mediated intramolecular N-N bond formation.

Publisher URL: http://feeds.rsc.org/~r/rss/ra/~3/Z9L35x8LPbY/C7RA06727E

DOI: 2017/RA/C7RA06727E

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