Trends in Biochemical Sciences
Trends in Biochemical Sciences
5 years ago

d-Tyrosyl-tRNA Deacylase: A New Function

d-Aminoacyl-tRNA deacylase (DTD) hydrolyzes d-amino acids mistakenly attached to tRNAs and, thus, has been implicated in perpetuating protein homochirality. Fifty years after the discovery of DTD, it has now been shown that its function extends beyond ‘chiral proofreading’ because it also eliminates glycine that has been erroneously coupled to tRNAAla.

Publisher URL: www.sciencedirect.com/science

DOI: S0968000417301305

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