Synthesis of 2-amino- and 2-arylazoazulenes via nucleophilic aromatic substitution of 2-chloroazulenes with amines and arylhydrazines

5 years ago

Synthesis of 2-amino- and 2-arylazoazulenes via nucleophilic aromatic substitution of 2-chloroazulenes with amines and arylhydrazines

Takanori Araki, Taku Shoji, Akira Ohta, Masafumi Yasunami, Shuhei Sugiyama, Shunji Ito, Shigeki Mori, Ryuta Sekiguchi, Tetsuo Okujima

The S_NAr reaction of 2-chloroazulene derivative 1 with ethoxycarbonyl groups at the 1,3-positions of the azulene ring with several amines afforded the corresponding 2-aminoazulenes 3-9 in excellent yields.

Publisher URL: http://feeds.rsc.org/~r/rss/OB/~3/WdktSFL3Nrg/C7OB00691H

DOI: 2017/OB/C7OB00691H

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