5 years ago

CuI-Catalyzed Fluorodesulfurization for the Synthesis of Monofluoromethyl Aryl Ethers

CuI-Catalyzed Fluorodesulfurization for the Synthesis of Monofluoromethyl Aryl Ethers
Yangjie Wu, Chengshan Niu, Dapeng Zou, Yang Geng, Yusheng Wu, Jingya Li, Apeng Liang, Xianying Gao
An efficient CuI-catalyzed fluorodesulfurization for the synthesis of monofluoromethyl aryl ethers using DAST at room temperature has been developed. This approach exhibits a good functional group tolerance, a broad substrate scope, and a high synthesis efficiency.

Publisher URL: http://dx.doi.org/10.1021/acs.joc.7b01438

DOI: 10.1021/acs.joc.7b01438

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