Journal of Physical Chemistry Letters
Journal of Physical Chemistry Letters
5 years ago

Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene

Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene
Kook-Han Kim, Bumjoon Choi, Nam Hyeong Kim, Bramaramba Gnapareddy, Young Hyun No, Seungwoo Lee, Young-Seon Ko, Yong-Tae Kim, Sung Ha Park, Sang Woo Lee, Sreekantha Reddy Dugasani, Yong Ho Kim, One-Sun Lee, Kilho Eom
Peptide assemblies have received significant attention because of their important role in biology and applications in bionanotechnology. Despite recent efforts to elucidate the principles of peptide self-assembly for developing novel functional devices, peptide self-assembly on two-dimensional nanomaterials has remained challenging. Here, we report nature-inspired two-dimensional peptide self-assembly on pristine graphene via optimization of peptide–peptide and peptide–graphene interactions. Two-dimensional peptide self-assembly was designed based on statistical analyses of >104 protein structures existing in nature and atomistic simulation-based structure predictions. We characterized the structures and surface properties of the self-assembled peptide formed on pristine graphene. Our study provides insights into the formation of peptide assemblies coupled with two-dimensional nanomaterials for further development of nanobiocomposite devices.

Publisher URL: http://dx.doi.org/10.1021/acs.jpclett.7b00996

DOI: 10.1021/acs.jpclett.7b00996

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.