ChemBioChem
ChemBioChem
5 years ago

A Boronic Acid Assay for the Detection of Mucin-1 Glycoprotein from Cancer Cells

A Boronic Acid Assay for the Detection of Mucin-1 Glycoprotein from Cancer Cells
Seung Joon Baek, Shiqiang Zhang, Michael D. Best, Xiaoyu Zhang
The back cover picture shows a sensitive, high-throughput platform for the detection of glycoproteins that are aberrantly expressed in disease, such as cancer-associated mucin-1. This assay, which enables the detection of mucin-1 directly from cancer cell lysates, entails the immobilization of carbohydrate-binding boronic acid moieties onto microplates coupled with chemiluminescence-based antibody analysis of surface-bound glycoproteins. More information can be found in the communication by M. D. Best et al. (DOI: 10.1002/cbic.201700288).

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/cbic.201700396

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