3 years ago

Aggregation-Induced Emission (AIE) Fluorophore Exhibits a Highly Ratiometric Fluorescent Response to Zn2+ in vitro and in Human Liver Cancer Cells

Aggregation-Induced Emission (AIE) Fluorophore Exhibits a Highly Ratiometric Fluorescent Response to Zn2+ in vitro and in Human Liver Cancer Cells
Hua Ma, Huimin Guo, Michael Watkinson, Ali Wajahat, Hassan Mehdi, Guiling Ning, Weitao Gong
A new AIE-active fluorophore that exhibits a rapid and highly selective ratiometric response to Zn2+ with a limit of detection (LOD) up to 2.6 nm is reported. Furthermore, the fluorophore was successfully applied in ratiometric imaging of intracellular Zn2+ in human hepatoma cancer cells by fluorescent confocal microscopy. More information can be found in the Full Paper by W. Gong, M. Watkinson, G. Ning et al. (DOI: 10.1002/chem.201701948).

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/chem.201703192

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