3 years ago

Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease

Ele Ferrannini, Alena Stančáková, Matthias Blüher, Jan Boren, Johanna Kuusisto, Adil Mardinoglu, Ulf Smith, Markku Laakso, Per Henrik Groop, Nicholas J. Wareham, Claudia Langenberg, Luca A. Lotta

Plasma mannose levels are elevated in subjects with insulin resistance independently of obesity. Here, we found that elevated plasma mannose levels are strong markers of future risk of several chronic diseases including T2D, CVD, and albuminuria, and that it may contribute to their development rather than just being a novel biomarker.

Publisher URL: http://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30427-8

DOI: 10.1016/j.cmet.2017.07.006

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