3 years ago

Energetic Basis of Single-Wall Carbon Nanotube Enantiomer Recognition by Single-Stranded DNA

Energetic Basis of Single-Wall Carbon Nanotube Enantiomer Recognition by Single-Stranded DNA
Akshaya Shankar, Anand Jagota, Ming Zheng
Hybrids of single-stranded DNA and single-walled carbon nanotubes (SWCNTs) have proven to be very successful in separating various chiralities and, recently, enantiomers of carbon nanotubes using aqueous two-phase separation. This technique sorts objects based on small differences in hydration energy, which is related to corresponding small differences in structure. Separation by handedness requires that a given ssDNA sequence adopt different structures on the two SWCNT enantiomers. Here we study the physical basis of such selectivity using a coarse-grained model to compute the energetics of ssDNA wrapped around an SWCNT. Our model suggests that difference by handedness of the SWCNT requires spontaneous twist of the ssDNA backbone. We also show that differences depend sensitively on the choice of DNA sequence.

Publisher URL: http://dx.doi.org/10.1021/acs.jpcc.7b05168

DOI: 10.1021/acs.jpcc.7b05168

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.