Asymmetric synthesis of chromene skeletons via organocatalytic domino reactions of in situ generated ortho-quinone methide with malononitrile and [small beta]-functionalized ketone

5 years ago

Asymmetric synthesis of chromene skeletons via organocatalytic domino reactions of in situ generated ortho-quinone methide with malononitrile and [small beta]-functionalized ketone

Wenjun Li, Pengfei Li, Lili Zhang, Yong Sun, Yang Liu, Xiao Zhou, Zhantao Liu

Enantioselective organocatalytic domino reactions of in situ generated ortho-quinone methides with malononitrile and [small beta]-functionalized ketones have been developed. This strategy could generate various chiral chromenes in high yields and stereoselectivities.

Publisher URL: http://feeds.rsc.org/~r/rss/ra/~3/oEb8_t560Wk/C7RA08157J

DOI: 2017/RA/C7RA08157J

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