3 years ago

Development of an electrochemical-surface plasmon dual biosensor based on carboxylated conducting polymer thin films

Development of an electrochemical-surface plasmon dual biosensor based on carboxylated conducting polymer thin films
Kazunari Shinbo, Futao Kaneko, Saengrawee Sriwichai, Keizo Kato, Tadashi Yamamoto, Sukon Phanichphant, Akira Baba, Rapiphun Janmanee
A biosensing platform based on the covalent attachment of biomolecules on electropolymerized carboxylated conducting polymers, poly(3-aminobenzoic acid) and poly(3-pyrrole carboxylic acid), were developed for the selective simultaneous detection of two biomolecules using electrochemical-surface plasmon resonance (EC–SPR) spectroscopy. The surface morphology of the developed biosensors was studied by scanning electron microscopy and atomic force microscopy. The EC–SPR dual biosensor was developed for the label-free, simultaneous, and selective detection of glucose and human immunoglobulin G (IgG). A change in current density was clearly observed after the injection of glucose, whereas a change in SPR reflectivity was clearly observed after the injection of human IgG. The present work demonstrates the potential of this biosensing platform for real sample analysis in the future. ©201X Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45641.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/app.45641

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