3 years ago

Gs protein peptidomimetics as allosteric modulators of the [small beta]2-adrenergic receptor

Gs protein peptidomimetics as allosteric modulators of the [small beta]2-adrenergic receptor
Xavier Kubiak, Tjerk J. Sminia, Phuong Thu Tran, Lotte-Emilie Boyhus, Soren G. F. Rasmussen, Daniel Sejer Pedersen, Jesper Mosolff Mathiesen, Kresten Lindorff-Larsen, Nina Smidt Bengtson, Mia Danielsen, Jacob Hartvig Loper, Micha Ben Achim Kunze
A series of Gs protein peptidomimetics were designed and synthesised based on the published X-ray crystal structure of the active state [small beta]2-adrenergic receptor ([small beta]2AR) in complex with the Gs protein (PDB 3SN6).

Publisher URL: http://feeds.rsc.org/~r/rss/ra/~3/hURbd1GSTYM/C7RA11713B

DOI: 2018/RA/C7RA11713B

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