Protein Science
Protein Science
5 years ago

MMM – A toolbox for integrative structure modelling

Gunnar Jeschke
Structural characterization of proteins and their complexes may require integration of restraints from various experimental techniques. MMM is a Matlab-based open-source modelling toolbox for this purpose with a particular emphasis on distance distribution restraints obtained from electron paramagnetic resonance experiments on spin-labelled proteins and nucleic acids and their combination with atomistic structures of domains or whole protomers, small-angle scattering data, secondary structure information, homology information, and elastic network models. MMM does not only integrate various types of restraints, but also various existing modelling tools by providing a common graphical user interface to them. The types of restraints that can support such modelling and the available model types are illustrated by recent application examples. This article is protected by copyright. All rights reserved.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/pro.3269

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