3 years ago

Linaclotide in Irritable Bowel Syndrome with Constipation: A Phase 3 Randomized Trial in China and Other Regions.

Youlin Yang, Xiaozhong Guo, Niwat Montreewasuwat, Mark G Currie, Xizhong Shen, Yunsheng Yang, Jingyuan Fang, Jeffrey M Johnston, Bal Raj Bhandari, Sam Lim, David S Reasner, Ning Dai, Peter Zeng, George Zhijian Chen, Jacquelyn A Cronin, Jing Sun
Linaclotide is a guanylate cyclase-C agonist approved in multiple countries to treat irritable bowel syndrome with constipation (IBS-C). China has unmet need for well-tolerated therapy that is effective in treating both bowel and abdominal symptoms of IBS-C. This trial evaluated linaclotide's efficacy and safety in IBS-C patients in China and other regions.

Publisher URL: http://doi.org/10.1111/jgh.14086

DOI: 10.1111/jgh.14086

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