Chemical Science
Chemical Science
5 years ago

Mass spectrometric directed system for the continuous-flow synthesis and purification of diphenhydramine

Mass spectrometric directed system for the continuous-flow synthesis and purification of diphenhydramine
Zoltan K. Nagy, David H. Thompson, R. Graham Cooks, Yanyang Hu, Andy Koswara, Bradley P. Loren, Kathryn Yammine, Michael Wleklinski
An integrated system utilizing mass spectrometry for reaction screening, continuous-flow optimization, and continuous crystallization of diphenhydramine has been developed.

Publisher URL: http://feeds.rsc.org/~r/rss/SC/~3/HunUA1q370Q/C7SC00905D

DOI: 2017/SC/C7SC00905D

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