3 years ago

Blockade of the Complement C5a/C5aR1 Axis Impairs Lung Cancer Bone Metastasis by CXCL16-mediated Effects.

Carlos Camps, María J Pajares, Ruben Pio, Fernando Lecanda, Sergio Ortiz-Espinosa, Leticia Corrales, Silvestre Vicent, Daniel Ajona, Fernando J de Miguel, Elena Martínez-Terroba, Naiara Perurena, Luis M Montuenga, Eloisa Jantus-Lewintre, Jackeline Agorreta, Haritz Moreno, Carolina Zandueta
C5aR1(CD88), a receptor for complement anaphylatoxin C5a, is a potent immune mediator. Its impact on malignant growth and dissemination of NSCLC cells is poorly understood.

Publisher URL: http://doi.org/10.1164/rccm.201703-0660OC

DOI: 10.1164/rccm.201703-0660OC

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