Shh-ushing Midline Crossing through Remote Protein Transport
Shh contributes to neural circuit formation with different mechanisms. In this issue, Peng and colleagues (2018) identify a novel trans-axonal mechanism by which Shh derived from contralateral projecting retinal ganglion cells prevents midline crossing of Boc-expressing ipsilateral axons at the optic chiasm.
Publisher URL: http://www.cell.com/neuron/fulltext/S0896-6273(18)30004-7
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