3 years ago

Long non-coding RNA LINC01619 regulates miR-27a/FOXO1 and endoplasmic reticulum stress-mediated podocyte injury in diabetic nephropathy.

Jian Geng, Xiaoting Liu, Jiao Wan, Jixing Liu, Xiao Li, Xiaoyan Bai, Zhan Mei Zhou
Altered activities of long non-coding RNAs (lncRNAs) have been implicated in the regulation of microRNAs. MicroRNA-27a (miR-27a) upregulation has been shown to induce endoplasmic reticulum stress (ER stress) and podocyte injury in diabetic nephropathy (DN). Herein, we aim to interrogate the mutually regulated network of miR-27a with long intergenic non-coding RNA 1619 (LINC01619) and the target gene.

Publisher URL: http://doi.org/10.1089/ars.2017.7278

DOI: 10.1089/ars.2017.7278

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