3 years ago

Cortical morphology development in patients with 22q11.2 deletion syndrome at ultra-high risk of psychosis.

Daniela Zöller, Maria Carmela Padula, Stephan Eliez, Elisa Scariati, Marie Schaer, Corrado Sandini, Marco Armando, Maude Schneider
Patients with 22q11.2 deletion syndrome (22q11DS) present a high risk of developing psychosis. While clinical and cognitive predictors for the conversion towards a full-blown psychotic disorder are well defined and largely used in practice, neural biomarkers do not yet exist. However, a number of investigations indicated an association between abnormalities in cortical morphology and higher symptoms severities in patients with 22q11DS. Nevertheless, few studies included homogeneous groups of patients differing in their psychotic symptoms profile.

Publisher URL: http://doi.org/10.1017/S0033291717003920

DOI: 10.1017/S0033291717003920

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