3 years ago

Prognostic Power of a Tumor Differentiation Gene Signature for Bladder Urothelial Carcinomas.

Zoe Tramel, Fengju Chen, Kazukuni Hayashi, Jianjun Shen, Yu-Cheng Lee, Qianxing Mo, Jing Xiao, Keith Syson Chan, Fotis Nikolos
Muscle-invasive bladder cancers (MIBCs) cause approximately 150 000 deaths per year worldwide. Survival for MIBC patients is heterogeneous, with no clinically validated molecular markers that predict clinical outcome. Non-MIBCs (NMIBCs) generally have favorable outcome; however, a portion progress to MIBC. Hence, development of a prognostic tool that can guide decision-making is crucial for improving clinical management of bladder urothelial carcinomas.

Publisher URL: http://doi.org/10.1093/jnci/djx243

DOI: 10.1093/jnci/djx243

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