Electrohydrodynamics of pressure-voltage-assisted polymer translocation.
We characterize the electrohydrodynamics of pressure-voltage-assisted polymer translocation events. Our theory can accurately reproduce and explain the experimentally measured translocation velocity and time of a DNA molecule in a pressure-voltage trap. The polymer dynamics is governed by the interplay between the streaming current, electrophoresis, and like-charge polymer-pore repulsion. The experimentally tunable conditions that maximally extend the duration of translocation events are identified. The emerging phase diagram provides the ideal characteristics for the optimal functioning of nanopore-based polymer sensing devices.
Publisher URL: http://arxiv.org/abs/1801.06140