3 years ago

Drug Delivery: Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug-Resistant Cancer Cells (Adv. Funct. Mater. 31/2017)

Drug Delivery: Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug-Resistant Cancer Cells (Adv. Funct. Mater. 31/2017)
Qingjie Ma, Da Han, Weihong Tan, Lin Liu, Zhongliang Wang, Ruili Zhang, Xiaoyuan Chen, Jie Tian, Shi Gao
An anti-MDR1 molecular-beacon-based micelle nanosystem is demonstrated by Zhongliang Wang, Qingjie Ma, Xiaoyuan Chen, and co-workers in article number 1701027. Owing to its ingenious design, the nanosystem is able to successfully administer both a MDR1 gene silencer and a chemotherapeutic agent in a sequential way to produce a synergistic therapeutic effect, enhancing chemotherapeutic efficacy to OVCAR8/ADR cells significantly.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/adfm.201770179

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.