Angewandte Chemie - International Edition
Angewandte Chemie - International Edition
5 years ago

An Unsaturated Quinolone N-Oxide of Pseudomonas aeruginosa Modulates Growth and Virulence of Staphylococcus aureus

An Unsaturated Quinolone N-Oxide of Pseudomonas aeruginosa Modulates Growth and Virulence of Staphylococcus aureus
Thomas Böttcher, Dávid Szamosvári
Chemical interactions of competing bacteria have major implications for health and disease of their human host. In their Communication (DOI: 10.1002/anie.201702944), D. Szamosvári and T. Böttcher report an unsaturated quinolone N-oxide produced by Pseudomonas aeruginosa with unprecedented efficacy and activity against Staphylococcus aureus affecting both growth and virulence. These results provide insight into a major metabolite by which P. aeruginosa modulates growth and behavior of its competitors.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/anie.201704012

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