3 years ago

Ultrasensitive SERS detection of propranolol based on sandwich nanostructure of molecular imprinting polymers

Ultrasensitive SERS detection of propranolol based on sandwich nanostructure of molecular imprinting polymers
Propranolol (PRO) is a β-blocker used in the treatment of heart disease. Recently, it has become a kind of organic pollutions due to its wide-spread use. However, the reliable and rapid analytical method for detection and monitoring PRO is still a challenge. We design a novel sandwich nanostructure for the specific and sensitive determination of trace propranolol in complex samples by surface enhanced Raman scattering technology. The sandwich nanostructure consists of graphene oxide/molecular imprinting polymers, target molecules, and sliver nanoparticles. This novel approach exhibits excellent sensitivity for propranolol, which makes the limit of detection as low as 10−11 mol/L. The results reveal the exceptional potential of the sandwich structure for high-performance environmental monitoring.

Publisher URL: www.sciencedirect.com/science

DOI: S0925400517314417

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