4 years ago

Ferric Heme-Nitrosyl Complexes: Kinetically Robust or Unstable Intermediates?

Ferric Heme-Nitrosyl Complexes: Kinetically Robust or Unstable Intermediates?
Nicolai Lehnert, Ashley B. McQuarters, E. Ercan Alp, Michael Hu, Jiyong Zhao, Jeff W. Kampf
We devised a convenient method for the preparation of ferric heme-nitrosyl, {FeNO}6, complexes, based on the bulk oxidation of corresponding ferrous {FeNO}7 precursors, and we have demonstrated this approach for tetraphenylporphyrin complexes. The obtained {FeNO}6 complexes show high solution stability in the absence of NO gas and were characterized using structural and spectroscopic methods. We prepared and crystallized the chloro complex [Fe(TPP)(NO)(Cl)], which represents a key intermediate in the autoreduction reaction of ferric hemes.

Publisher URL: http://dx.doi.org/10.1021/acs.inorgchem.7b01493

DOI: 10.1021/acs.inorgchem.7b01493

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.