Crystal Growth & Design
Crystal Growth & Design
5 years ago

Liquid Nicotine Tamed in Solid Forms by Cocrystallization

Liquid Nicotine Tamed in Solid Forms by Cocrystallization
Katia Rubini, Alessia Bacchi, Paolo P. Mazzeo, Paolo Pelagatti, Davide Balestri, Davide Capucci
Pure nicotine is a liquid. We stabilized it in solid form by cocrystallization; three nicotine cocrystals have been designed by considering the molecular electrostatic potential characteristic. The structural role of coformers in driving cocrystallization is investigated by energy frameworks analyses.

Publisher URL: http://dx.doi.org/10.1021/acs.cgd.7b00887

DOI: 10.1021/acs.cgd.7b00887

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