3 years ago

Towards the use of monofluorinated dimyristoylphosphatidylcholines as 19F NMR reporters in bacterial model membranes

Towards the use of monofluorinated dimyristoylphosphatidylcholines as 19F NMR reporters in bacterial model membranes
We report biophysical studies of novel fluorine-labelled prokaryotic cell model membranes aiming to be used as NMR reporters for the study of biomolecule complexes. FTIR studies of F-DMPC/DMPC/DMPG tertiary mixtures were carried out at various fluorinated lipid/non-fluorinated lipid and PC/PG ratio. Preliminary solid-state static 19F- and 31P-NMR analyses are also reported and confirmed that those mixed bilayers could be used as bacterial model membranes to study interactions with biomolecules in NMR spectroscopy.

Publisher URL: www.sciencedirect.com/science

DOI: S0022113917304918

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