Organometallics
Organometallics
5 years ago

NHTs Effect on the Enantioselectivity of Ru(II) Complex Catalysts Bearing a Chiral Bis(NHTs)-Substituted Imidazolyl-Oxazolinyl-Pyridine Ligand for Asymmetric Transfer Hydrogenation of Ketones

NHTs Effect on the Enantioselectivity of Ru(II) Complex Catalysts Bearing a Chiral Bis(NHTs)-Substituted Imidazolyl-Oxazolinyl-Pyridine Ligand for Asymmetric Transfer Hydrogenation of Ketones
Huining Chai, Tingting Liu, Zhengkun Yu
Pincer-type ruthenium(II)-NNN complex catalysts bearing a chiral bis(NHTs)-substituted imidazolyl-oxazolinyl-pyridine ligand were synthesized and structurally characterized by NMR, IR, elemental analysis, and X-ray single-crystal crystallographic determinations. The two NHTs groups substituted on the imidazolyl moiety of the chiral NNN ligand exhibited a remarkable effect on the enantioselectivity of the Ru(II)-NNN complexes for the asymmetric transfer hydrogenation (ATH) of ketones. The Ru(II)-NNN complex bearing a chiral (NHTs)2-substituted imidazolyl-(isopropyl)oxazolinyl-pyridine ligand exhibited excellent catalytic activity, reaching an enantioselectivity up to 99.9% ee for the target alcohol products.

Publisher URL: http://dx.doi.org/10.1021/acs.organomet.7b00559

DOI: 10.1021/acs.organomet.7b00559

You might also like
Discover & Discuss Important Research

Keeping up-to-date with research can feel impossible, with papers being published faster than you'll ever be able to read them. That's where Researcher comes in: we're simplifying discovery and making important discussions happen. With over 19,000 sources, including peer-reviewed journals, preprints, blogs, universities, podcasts and Live events across 10 research areas, you'll never miss what's important to you. It's like social media, but better. Oh, and we should mention - it's free.

  • Download from Google Play
  • Download from App Store
  • Download from AppInChina

Researcher displays publicly available abstracts and doesn’t host any full article content. If the content is open access, we will direct clicks from the abstracts to the publisher website and display the PDF copy on our platform. Clicks to view the full text will be directed to the publisher website, where only users with subscriptions or access through their institution are able to view the full article.