3 years ago

Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke.

Velandai K Srikanth, Megan A Evans, Antony Vinh, Silke Neumann, Vanessa H Brait, Christopher T Chan, Brad R S Broughton, Sarah Young, Luting Poh, Hannah X Chu, James A Bourne, Colin W Pouton, Andrew N Clarkson, Rebecca Lim, Christopher G Sobey, Leon Teo, John M Haynes, Cameron P J Hunt, Chantelle V Gardiner-Mann, Thanh G Phan, Hyun Ah Kim, Emma K Gowing, Quynh Nhu Dinh, Kimberly W E Taylor, Henry Ma, Grant R Drummond, William Kwan, Euan M Wallace, Thiruma V Arumugam, Stavros Selemidis, David Y Fann, Seyoung Lee
Human amnion epithelial cells (hAECs) are nonimmunogenic, nontumorigenic, anti-inflammatory cells normally discarded with placental tissue. We reasoned that their profile of biological features, wide availability, and the lack of ethical barriers to their use could make these cells useful as a therapy in ischemic stroke.

Publisher URL: http://doi.org/10.1161/STROKEAHA.117.019136

DOI: 10.1161/STROKEAHA.117.019136

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