CuII complex of emodin with improved anticancer activity as demonstrated by its performance on HeLa and Hep G2 cells

5 years ago

CuII complex of emodin with improved anticancer activity as demonstrated by its performance on HeLa and Hep G2 cells

Sanjay Kumar, Sanjoy Kumar Dey, Bitapi Mandal, Saurabh Das, Swagata Mazumdar, Parimal Karmakar, Soumen Singha

Structure of Cu^II complex of emodin was solved from PXRD data. [Cu^II(emod)₂]^2- binds DNA better than emodin. Thermodynamic parameters for binding were found. Complex performs better than emodin on HeLa & Hep G2 cells; not affecting WI 38 normal cells.

Publisher URL: http://feeds.rsc.org/~r/rss/ra/~3/nJa4pmr-Jrc/C7RA06696A

DOI: 2017/RA/C7RA06696A

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