Cancer Evolution Constrained by the Immune Microenvironment
Tumor development is a Darwinian evolutionary process, involving the interplay between cancer subclones and the local immune microenvironment. These complex interactions are highlighted in this issue of Cell by the results from Jiménez-Sánchez et al. of a deep analysis of one patient with advanced serous carcinoma of the ovary.
Publisher URL: http://www.cell.com/cell/fulltext/S0092-8674(17)30937-6
DOI: 10.1016/j.cell.2017.08.012
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