Clinical Cancer Research
Clinical Cancer Research
5 years ago

Metastasis seeding cells: Lone invaders or mass migrators?

Marco Gerlinger
Lymph node metastases are among the best predictors of recurrence and of cancer related death in early stage colorectal cancers. Yet, despite their clinical and biological relevance, it remains elusive how lymph node metastases develop and whether metastatic seeding is a major bottleneck that restrains genetic heterogeneity of metastatic disease.

Publisher URL: http://doi.org/10.1158/1078-0432.CCR-17-3644

DOI: 10.1158/1078-0432.CCR-17-3644

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