Electrophoresis
Electrophoresis
5 years ago

Inside Front Cover: Electropreconcentration-induced local pH change

Inside Front Cover: Electropreconcentration-induced local pH change
Honggu Chun
DOI: 10.1002/elps.201700373The cover picture shows the anion-selective electropreconcentration mechanism as well as the concentrating process with an anionic pH indicator, phenol red, as the sample. Contrary to the widely accepted knowledge in the academic society, the electropreconcentration is charge-selective. One of inevitable phenomena due to the charge-selectivity is radical pH change (up to 4 units) in the preconcentrated sample plug. Therefore, careful design and interpretation are required when the electropreconcentration is coupled with pH-dependent experiments such as analyzing enzyme or antibody characteristics.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/elps.201870022

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