Electrophoresis
Electrophoresis
5 years ago

Back Cover: Parallel probing of drug uptake of single cancer cells on a microfluidic device

Back Cover: Parallel probing of drug uptake of single cancer cells on a microfluidic device
Hoon Suk Rho, Leon WMM Terstappen, Séverine Le Gac, Yoonsun Yang
DOI: 10.1002/elps.201700351The cover picture shows a microfluidic device to investigate drug uptake by single cancer cells. The device is capable of isolating individual cells from a cell suspension into reaction chambers and exposing the cells to different concentrations of a target drug. The potential of the device was demonstrated by showing the increase of intracellular fluorescence intensity and nuclear localization of the fluorescent drug doxorubicin with increasing drug dose of single cancer cells.

Publisher URL: http://onlinelibrary.wiley.com/resolve/doi

DOI: 10.1002/elps.201870025

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